Source: News Rx

A new study, 'Cellular therapy of systemic lupus erythematosus,' is now available. "Immunoablation with autologous hematopoietic stem cell rescue has been used in over 1,300 autoimmune disease patients, around 150 with SLE. Some patients have experienced durable remissions with loss of autoantibodies, whereas others either did not respond or died as a result of the treatment," scientists writing in the journal Lupus report.

"Prospective randomised trials are required and are being planned to establish the place for this potentailly curative strategy. Mesenchymal stem cells are in an exploratory phase for the treatment of acute autoimmune disease including SLE," wrote A. Tyndall and colleagues, University of Basel, Department of Rheumatology.

The researchers concluded: "The principle is that they home to inflammed tissue and exert an antiinflammatory paracrine effect."

Tyndall and colleagues published their study in Lupus (Cellular therapy of systemic lupus erythematosus. Lupus, 2009;18(5):387-93).

Additional information can be obtained by contacting A. Tyndall, Felix Platter Hospital, Dept. of Rheumatology, University of Basel, 4012, Basel, Switzerland.

The publisher of the journal Lupus can be contacted at: SAGE Publications, USA , 2455 Teller Road, Thousand Oaks, CA 91320, USA.

Keywords: Switzerland, Basel, Lupus Therapy, Autoimmune Disease, Autoimmune Disorder, Hematology, Hematopoietic, Immunology, Rheumatology, Stem Cell Research, Systemic Lupus Erythematosus, Therapy, Treatment.

This article was prepared by NewsRx editors from staff and other reports. Copyright 2009, NewsRx.com.